![118 Re36H44N2O8Si Uridine, 5'-O-[bis(4-metoksîfenîl)fenîlmethyl]-2'-O-[(1,1-dimetîlethyl)dimethylsilyl]- (9CI, ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![118 Re36H44N2O8Si Uridine, 5'-O-[bis(4-methoksyphenyl)fenylmethyl]-2'-O-[(1,1- dimethylethyl)dimethylsilyl]- (9CI, ACI) Wêne diyar](https://cdn.globalso.com/nvchem/118-Re36H44N2O8Si-Uridine.jpg)
118 Re36H44N2O8Si Uridine, 5'-O-[bis(4-metoksîfenîl)fenîlmethyl]-2'-O-[(1,1-dimetîlethyl)dimethylsilyl]- (9CI, ACI)
| Taybetmendiyên fizîkî yên sereke | Giranî | Rewş |
| Giraniya molekulî | 660.83 | - |
| Density (Pêşbîn kirin) | 1,24±0,1 g/cm3 | Germ: 20 °C; Çapemenî: 760 Torr |
| pKa (Pêşbînî kirin) | 9,39±0,10 | Germahiya herî asîdî: 25 °C |
PÊŞÎNÊN kanonîkî O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C= C5)C(O)C2O[Si](C)(C)C(C)(C)C
SMILES Îzomerî
C(OC[C@H]1O[C@H]([C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O)N2C( =O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
InChI
InChI=1S/C36H44N2O8Si/c1-35(2,3)47(6,7)46-32-31(40)29(45-33(32)38-22-21-30(39)37-34( 38)41)23-44-36(24-11-9-8-10-12-24,25-13- 17-27(42-4)18-14-25)26-15-19-28( 43-5)20-16-26/h8-22,29,31-33,40H,23H2,1-7H3,(H,37,39,41)/t29-,31-,32-,33-/ m1/s1
InChI Key
KVHQIELPHWJPSY-WXQJYUTRSA-N
2 Navên din ên vê madeyê
5'-O-[Bis(4-metoksîfenîl)fenîlmethyl]-2'-O-[(1,1-dimetîlethyl)dimetîlsilîl]ûrîdîn (ACI); 2'-O-tert-Butyldimethylsilyl-5'-O-(4,4'-dimetoksytrityl)uridine
Spectra heye
1H NMR
13C NMR
Hetero NMR
Gel
| Taybetmendiyên berdest |
| Biyolojîkî |
| Şîmyakî |
| Density |
| Lipinski |
| Structure Related |
Biyolojîkî
| Mal | Giranî | Rewş | Kanî |
| Faktora Bioconcentration | 2,21 x 105 | pH 1; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,21 x 105 | pH 2; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,21 x 105 | pH 3; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,21 x 105 | pH 4; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,21 x 105 | pH 5; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,21 x 105 | pH 6; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,20 x 105 | pH 7; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 2,12 x 105 | pH 8; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 1,54 x 105 | pH 9; Germ: 25 °C | (1) ACD |
| Faktora Bioconcentration | 42500 | pH 10; Germ: 25 °C | (1) ACD |
(1) Bi karanîna Nermalava Pêşveçûna Kîmyaya Pêşkeftî (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs) tê hesab kirin
Şîmyakî
| Mal | Giranî | Rewş | Kanî |
| Koc | 2,33 x 105 | pH 1; Germ: 25 °C | (1) ACD |
| Koc | 2,33 x 105 | pH 2; Germ: 25 °C | (1) ACD |
| Koc | 2,33 x 105 | pH 3; Germ: 25 °C | (1) ACD |
| Koc | 2,33 x 105 | pH 4; Germ: 25 °C | (1) ACD |
| Koc | 2,33 x 105 | pH 5; Germ: 25 °C | (1) ACD |
| Koc | 2,33 x 105 | pH 6; Germ: 25 °C | (1) ACD |
| Mal | Giranî | Rewş | Kanî |
| Koc | 2,32 x 105 | pH 7; Germ: 25 °C | (1) ACD |
| Koc | 2,23 x 105 | pH 8; Germ: 25 °C | (1) ACD |
| Koc | 1,62 x 105 | pH 9; Germ: 25 °C | (1) ACD |
| Koc | 44800 | pH 10; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 1; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 2; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 3; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 4; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 5; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 6; Germ: 25 °C | (1) ACD |
| logD | 7.33 | pH 7; Germ: 25 °C | (1) ACD |
| logD | 7.32 | pH 8; Germ: 25 °C | (1) ACD |
| logD | 7.18 | pH 9; Germ: 25 °C | (1) ACD |
| logD | 6.62 | pH 10; Germ: 25 °C | (1) ACD |
| logP | 7,334±0,643 | Germ: 25 °C | (1) ACD |
| Mass Intrinsic Çareseriya | 3,5 x 10-5 g/L | Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 1; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 2; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 3; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 4; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 5; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 6; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH 7; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,6 x 10-5 g/L | pH 8; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 5,0 x 10-5 g/L | pH 9; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 1,9 x 10-4 g/L | pH 10; Germ: 25 °C | (1) ACD |
| Çareseriya girseyî | 3,5 x 10-5 g/L | pH ava nebuffered 7,00; Germ: 25 °C | (1) ACD |
| Çareseriya Xweseriya Molar | 5,3 x 10-8 mol/L | Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 1; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 2; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 3; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 4; Germ: 25 °C | (1) ACD |
| Mal | Giranî | Rewş | Kanî |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 5; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 6; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH 7; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,5 x 10-8 mol/L | pH 8; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 7,6 x 10-8 mol/L | pH 9; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 2,8 x 10-7 mol/L | pH 10; Germ: 25 °C | (1) ACD |
| Çareseriya Molar | 5,3 x 10-8 mol/L | pH ava nebuffered 7,00; Germ: 25 °C | (1) ACD |
| Giraniya molekulî | 660.83 | ||
| pKa | 9,39±0,10 | Germahiya herî asîdî: 25 °C | (1) ACD |
(1) Bi karanîna Nermalava Pêşveçûna Kîmyaya Pêşkeftî (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs) tê hesab kirin
Density
| Mal | Giranî | Rewş | Kanî |
| Density | 1,24±0,1 g/cm3 | Germ: 20 °C; Çapemenî: 760 Torr | (1) ACD |
| Volume Molar | 528,8±5,0 cm3/mol | Germ: 20 °C; Çapemenî: 760 Torr | (1) ACD |
(1) Bi karanîna Nermalava Pêşveçûna Kîmyaya Pêşkeftî (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs) tê hesab kirin
Lipinski
| Mal | Giranî | Rewş | Kanî |
| Bonds Bi Azadî Rotable | 13 | (1) ACD | |
| H Qebûrker | 10 | (1) ACD | |
| H Donors | 2 | (1) ACD | |
| H Donor / Qebûl Sum | 12 | (1) ACD | |
| logP | 7,334±0,643 | Germ: 25 °C | (1) ACD |
| Giraniya molekulî | 660.83 |
(1) Bi karanîna Nermalava Pêşveçûna Kîmyaya Pêşkeftî (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs) tê hesab kirin
Structure Related
| Mal | Giranî | Rewş | Kanî |
| Qada Rûyê Polar | 116 A2 | (1) ACD | |
(1) Bi karanîna Nermalava Pêşveçûna Kîmyaya Pêşkeftî (ACD/Labs) V11.02 (© 1994-2023 ACD/Labs) tê hesab kirin
Spectra heye
1H NMR
13C NMR
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